PROCHASSON Philippe
Postdoctoral research Fellow of the
Leukemia and Lymphoma Society
Workman's Lab
Stowers Insitute for Medical Research
1000 E. 50th street
Kansas City, MO. 64110
Phone: (816) 926-4312
Fax: (816) 926-4686
E-mail: philippe@prochasson.com or psp@stowers-institute.org

July 2003 -present	PostDoctoral Research Fellow of the Leukemia and Lymphoma Society Stowers Insitute for Medical Research. 1000 E. 50th street, Kansas City, MO. 64110. Jerry Workman Lab
March 2001-July 2003	PostDoctoral Associate of the Howard Hughes Medical Institute. Jerry L. Workman's Lab, Department of Biochemistry and Molecular Biology, 306 Althouse Laboratory, The Pennsylvania State University, University Park, PA 16802.
2000	Doctorate University Paris XI . Institut Gustave Roussy, Laboratoire de Genetique Oncologique UMR 1599, Villejuif, France. Subject: Study of transcriptional mechanisms responsible for the differential expression of the keratin 18 gene between tumorigenic and non-tumorigenic cells of human colon carcinoma cell line. Defended on the 15th of december 2000 .
1995	M.Sc. in Fondamental Bases of Oncogenesis, University Paris XI , France. D.E.A. de Bases Fondamentales de l'Oncogenese.
1994	B.Sc. in  Molecular Biology and Genetic, University Paris XI , Orsay, France. Certificates: Molecular Biology, Biochemistry, Physiology, Genetic , Development biology, Evolution.

9	Prochasson, P., Florens, L., Swanson, S.K., Washburn, M.P., and Workman, J.L. (2005). The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21): 2534-2539
8	Ferreira ME, Hermann S, Prochasson P, Workman JL, Berndt KD, Wright AP. Mechanism of transcription factor recruitment by acidic activators. J Biol Chem. 2005 Jun 10;280(23):21779-84.
7	Delouis C, Prochasson P, Laithier M, Brison O. Use of adenoviral E1A protein to analyze K18 promoter deregulation in colon carcinoma cells discloses a role for CtBP1 and BRCA1. BMC Mol Biol. 2005 Apr 14;6(1):8.
6	Lee KK, Prochasson P, Florens L, Swanson SK, Washburn MP, Workman JL. Proteomic analysis of chromatin-modifying complexes in Saccharomyces cerevisiae identifies novel subunits. Biochem Soc Trans. 2004 Dec;32(Pt 6):899-903.
5	Philippe Prochasson, Kristen E. Neely, Ahmed H. Hassan, Bing Li and Jerry L. Workman Targeting activity is required for SWI/SNF function in vivo and is accomplished through two partially redundant activator interaction domains. Mol Cell. 2003 Oct;12(4):983-90. PDF file
4	Ahmed H. Hassan, Philippe Prochasson, Kristen E. Neely, Scott C. Galasinski, Mark Chandy, Michael J. Carrozza and Jerry L. Workman Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes. Cell. 2002 Nov 1;111(3):369-79.
3	P. Prochasson, C. Delouis and O. Brison. Transcriptional deregulation of the keratin 18 gene in human colon carcinoma cells results from an altered acetylation mechanism. Nucleic Acids Res. 2002 Aug 1;30(15):3312-22.
2	N. Fossar, M. Chaouche, P. Prochasson, M. Rousset and O. Brison. Deregulated expression of the keratin 18 gene in human colon carcinoma cells. Somat Cell Mol Genet. 2001 Jul;25(4):223-35.
1	P. Prochasson, M. Gunther, M. Laithier, N. Fossar, C. Lavialle and O. Brison. Transcriptional mechanisms responsible for the differential expression of the cytokeratin 18 gene between tumorigenic and non tumorigenic cells of human colon carcinoma cell line. Experimental Cell Research 248 , 243-259 (1999) .

13	Philippe Prochasson, Laurence Florens, Selene Swanson, Michael P. Washburn and Jerry L. Workman. The Histone Regulation (HIR) co-repressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. (Poster). 2005 Stohlman Scholar Symposium. Scottsdale, Arizona, USA. September 23-25, 2005.
12	Philippe Prochasson, Laurence Florens, Mike P. Washburn and Jerry L. Workman. The HIR co-repressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF (Poster). Keystone Symposium - Chromatin Modification Pathways. Snowbird, Utah, USA March 31 – April 5, 2005.
11	Study of the chromatin remodeling SWI/SNF complex in yeast. (Invited speaker, lay audience) New Horizons in the Treatment of Blood Cancers. The Leukemia and Lymphoma Society. St Joseph Health Center, Kansas City, MO. February 19th, 2005.
10	Philippe Prochasson, Laurence Florens, Mike P. Washburn and Jerry L. Workman. The HIR co-repressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. (Poster). 2004 Stohlman Scholar Symposium. Denver, Colorado, USA. November 11-12, 2004.
9	Prochasson, P., Neely, K.E., Hassan, A.H., Workman, J.L. Targeting activity is required for SWI/SNF function in vivo and is accomplished through two partially redundant activator interaction domains. (Poster) Mechanisms of Eukaryotic Transcription. Cold Spring Harbor Laboratory, New-York, USA. August 27-31, 2003.
8	Prochasson, P., Neely, K.E., Hassan, A.H., Workman, J.L. Targeting Activity is Required for SWI/SNF Function In Vivo (Platform presentation) 22th Summer Symposium in Molecular Biology:  Chromatin Structure & Function. Pennsylvania State University, University Park, PA. July 30-August 2, 2003
7	Prochasson, P., Neely, K.E., Carrozza, M.J., Hassan, A.H., Workman, J.L. Activator Interactions are Required for SWI/SNF Function In Vivo (Poster). Fifth EMBL Transcription Meeting, Heidelberg, Germany, August 24-28, 2002
6	Philippe Prochasson and Olivier Brison. Alterations in Acetylation Mechanisms Involving the p300/CBP Proteins in Human Colon Carcinoma Cells (Poster). Fourth EMBL Transcription Meeting . Heidelberg, Germany, August 26-30, 2000.
5	Philippe Prochasson , Anna Polesskaya and Olivier Brison. Alterations in Acetylation Regulatory Mechanisms Contribute to Transcriptional Deregulation of the Keratin 18 Gene in Human Colon Carcinoma Cells (Poster ). Premières Journées André Lwoff. Chromatin and cell cycle: open questions. Villejuif, France , November 8-9, 1999.
4	Mechanisms of Eukaryotic Transcription. Cold Spring Harbor Laboratory, New-York, USA. September 1-5, 1999.
3	Dérégulation transcriptionnelles dans des cellules de carcinome du colon humain: rôle de l'acétylation. (Oral Presentation) Seminar of Pole n°2 "Biologie et Génétique des Tumeurs". Institut Gustave Roussy, Villejuif , 16 avril 1999.
2	P. Prochasson, M. Gunther, C. Lavialle and O. Brison. Overexpression of the K18 gene in tumorigenic cells of a human colon carcinoma cell line (Poster). Third EMBL Transcription meeting. Heidelberg, Germany, August 22-26, 1998.
1	P. Prochasson, M. Gunther, C. Lavialle and O. Brison. Transcriptional mechanisms responsible for the differential expression of the cytokeratin 18 gene between tumorigenic and non tumorigenic cells of human colon carcinoma cell line (Poster). Keystone Symposium - Epigenetic regulation of transcription . Copper Mountain, Colorado, USA. April 4-9, 1998.

2006	Awarded a Leukemia & Lymphoma Society Special Fellow Award (Starting July 2006, 3 years)
2005	Keystone Symposia Scholarship
July 2003  to present	PostDoctoral Research Fellow of the Leukemia and Lymphoma Society
1998 to 2000	Recipient of La Ligue contre le Cancer Scholarship, comite de l'Essonne , France.

10/1999 to 12/2000	Cecile Delouis, DEA Cellules Normales et Pathologiques (5th year of university, Master Student), University of Paris V.
07/1999 to 09/1999	Stephane Daffis, intern of Magistere de Génétique (3rd year of university, BS student), University of Paris VII.
07/1999 to 09/1998	Erwan Le Scolan, intern of Licence de Biochimie (3rd year of university, BS student) University of Paris VI.

Dr Jerry Workman	Stowers Insitute for Medical Research 1000 E. 50th street Kansas City, MO. 64110 Email: jlw@stowers-institute.org Phone:  (816) 926-4312, Fax: (816) 926-4690
Dr Olivier Brison	UMR 7147 Section de Recherche Institut Curie. 26 rue d'Ulm, 75248 Paris cedex 05. Email: olivier.brison@curie.fr Phone: +33 (0)1 42 34 66 70 Fax: +33 (0)1 42 34 66 74
Joan W. Conaway Ph.D., Senior Scientist Ron C. Conaway Ph.D., Senior Scientist	Stowers Institute for Medical Research 1000 E. 50th street, Kansas City, MO. 64110 Email: jlc@stowers-institute.org, Email: rcc@stowers-institute.org Phone: jlc: 816-926-4091, rcc: 816-926-4092 Fax: 816-926-2093
Paul D. Kaufman Ph.D., Associate Professor	Program in Gene Function and Expression University of Massachusetts Medical School LRB 506, 364 Plantation Street, Worcester, MA 01605-2324 Email: paul.kaufman1@umassmed.edu Phone (508) 856-5016.
Dr Jean Feunteun	Institut G-Roussy. Laboratoire de Genetique Oncologique . 39 rue Camille Desmoulins. 94805 Villejuif Cedex-France. E-mail: feunteun@igr.fr Phone : 33 (1) 42 11 42 94, Fax: 33 (1) 42 11 52 61

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