PROCHASSON Philippe
Howard Hughes Medical Institute
Department of Biochemistry and Molecular Biology
Workman's Lab
306 Althouse Laboratory
The Pennsylvania State University
University Park, PA 16802
Tel.: (814) 863-8554
Fax: (814) 863-0099
E-mail: philippe@prochasson.com or psp10@psu.edu
21/01/1972
Marié

depuis Mars 2001	PostDoc Associate Howard Hughes Medical Institute dans le laboratoire de Jerry L. Workman, Department of Biochemistry and Molecular Biology , 306 Althouse Laboratory, The Pennsylvania State University , University Park, PA 16802.
2000	Doctorat de l’ Universite Paris XI . Spécialité: Bases Fondamentales de l’Oncogenèse Sujet: Mécanismes Transcriptionnels de la Surexpression du Gène de la Kératine 18 dans des Cellules de Carcinome du Colon Humain . Soutenue le 15 decembre 2000 .
1995	D.E.A. de Bases Fondamentales de l'Oncogenese , Universite Paris XI .
1994	Maîtrise de Biologie Moléculaire et Génétique , Universite Paris XI , Orsay. Génétique Moléculaire (B) Biologie du Développement (B), Biochimie (AB), Evolution.
1993	Licence de Biochimie, Universite Paris XI , Orsay . Biologie Moléculaire (TB), Biochimie (B), Physiologie Animale (B), Génétique.
1992	DEUG Sciences Naturelles, option Biologie. Faculté des Sciences du Maine, Le Mans. Mention AB.

2002	Ahmed H. Hassan, Philippe Prochasson, Kristen E. Neely, Scott C. Galasinski, Mark Chandy, Michael J. Carrozza and Jerry L. Workman FUNCTION AND SELECTIVITY OF BROMODOMAINS IN ANCHORING CHROMATIN-MODIFYING COMPLEXES TO PROMOTER NUCLEOSOMES Cell in press
2002	P. Prochasson, C. Delouis and O. Brison. Transcriptional deregulation of the keratin 18 gene in human colon carcinoma cells results from an altered acetylation mechanism. Nucleic Acids Res. 2002 Aug 1;30(15):3312-22.
2001	N. Fossar, M. Chaouche, P. Prochasson, M. Rousset and O. Brison. Deregulated expression of the keratin 18 gene in human colon carcinoma cells. Somat Cell Mol Genet. 2001 Jul;25(4):223-35.
1999	P. Prochasson, M. Gunther, M. Laithier, N. Fossar, C. Lavialle and O. Brison. Transcriptional mechanisms responsible for the differential expression of the cytokeratin 18 gene between tumorigenic and non tumorigenic cells of human colon carcinoma cell line. Experimental Cell Research 248 , 243-259 (1999) .

2002	Prochasson, P., Neely, K.E., Carrozza, M.J., Hassan, A.H., Workman, J.L. Activator Interactions are Required for SWI/SNF Function In Vivo (Poster). Fifth EMBL Transcription Meeting, Heidelberg, Germany, August 24-28, 2002
2000	Philippe Prochasson and Olivier Brison. Alterations in Acetylation Mechanisms Involving the p300/CBP Proteins in Human Colon Carcinoma Cells (Poster). Fourth EMBL Transcription Meeting . Heidelberg, Germany, August 26-30, 2000.
1999	Philippe Prochasson , Anna Polesskaya and Olivier Brison. Alterations in Acetylation Regulatory Mechanisms Contribute to Transcriptional Deregulation of the Keratin 18 Gene in Human Colon Carcinoma Cells (Poster ). Premières Journées André Lwoff. Chromatin and cell cycle: open questions. Villejuif, France , November 8-9, 1999.
1999	Mechanisms of Eukaryotic Transcription. Cold Spring Harbor Laboratory, New-York, USA. September 1-5, 1999.
1999	Dérégulation transcriptionnelles dans des cellules de carcinome du colon humain: rôle de l'acétylation. Seminaire du Pole n°2 "Biologie et Génétique des Tumeurs". Institut Gustave Roussy, Villejuif , 16 avril 1999.
1998	P. Prochasson, M. Gunther, C. Lavialle and O. Brison. Overexpression of the K18 gene in tumorigenic cells of a human colon carcinoma cell line (Poster). Third EMBL Transcription meeting . Heidelberg, Germany, August 22-26, 1998.
1998	P. Prochasson, M. Gunther, C. Lavialle and O. Brison. Transcriptional mechanisms responsible for the differential expression of the cytokeratin 18 gene between tumorigenic and non tumorigenic cells of human colon carcinoma cell line (Poster). Keystone Symposium - Epigenetic regulation of transcription . Copper Mountain, Colorado, USA. April 4?9, 1998.

2002	PostDoc Associate de  Howard Hughes Medical Institute.
2001	PostDoc Associate de  Howard Hughes Medical Institute.
2000	Bourse de La Ligue contre le Cancer, comité de l'Essonne , France.
1999	Bourse de La Ligue contre le Cancer, comité de l'Essonne , France.
1998	Bourse de La Ligue contre le Cancer, comité de l'Essonne , France.

Biologie Moléculaire et Biochimie :	Chromatographie, systeme AKTA, FPLC et Smart System Northern et Southern blot analysis Polymerase Chain Reaction (PCR) Electrophoretic Mobility Shift Assay In vitro Transcription Nuclear Run-On RNase Mapping Primer Extension Sequence Western blot analysis Immunoprecipitation Acid-Urea-Triton gel electrophoresis Histone Acetyl Transferase (HAT) Assay CAT and Luciferase Assays
Biologie Cellulaire :	Culture Cellulaire Transfections Transitoires et Stables Genetique de la levure

10/1999 to 02/2001	Responsable de stage de DEA de: Cecile Delouis, DEA Cellules Normales et Pathologiques, Université Paris V.
07/1999 to 09/1999	Stephane Daffis, stagiaire du Magistere de Génétique, Université Paris VII.
07/1999 to 09/1998	Erwan Le Scolan, stagiaire de Licence de Biochimie, Université Paris VI.

Dr Jerry Workman :	Paul Berg Professor of Biochemistry. Howard Hughes Medical Institute . Department of Biochemistry and Molecular Biology . 306 Althouse Laboratory. The Pennsylvania State University . University Park, PA 16802 E-mail: jlw10@psu.edu Tel: (814) 863-8256, Fax: (814) 863-0099
Dr Olivier Brison :	Institut G-Roussy. Laboratoire de Genetique Oncologique . 39 rue Camille Desmoulins. 94805 Villejuif Cedex-France. E-mail: obrison@igr.fr Tel: 33 (1) 42 11 54 13, Fax: 33 (1) 42 11 52 61
Dr Jean Feunteun :	Institut G-Roussy. Laboratoire de Genetique Oncologique . 39 rue Camille Desmoulins. 94805 Villejuif Cedex-France. E-mail: feunteun@igr.fr Tel: 33 (1) 42 11 42 94, Fax: 33 (1) 42 11 52 61
Dr Jean Benard :	Institut G-Roussy. Laboratoire des marqueurs genetique de cancer. 39 rue Camille Desmoulins. 94805 Villejuif Cedex-France. E-mail: benard@igr.fr Tel: 33 (1) 42 11 48 18, Fax: 33 (1) 42 11 52 80

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